In the field of medical imaging, clear observation of bone structures is critical for disease diagnosis and treatment. recently,A scientific research team from the Chinese Academy of Sciences has made a major breakthrough - the invention of a new fluorescent probe that can make bones "glow" and achieve a clear presentation of bone conditions.

This new fluorescent probe uses near-infrared second-band light with a wavelength of 900nm–1700nm, which can penetrate biological tissues more effectively and reduce background interference.


New fluorescent probe molecules

The research team used these fluorescent molecules to conduct a "whole body examination" on the experimental mice.Not only can we see the conditions of multiple organs in the mouse's body, but we can also observe the metabolic processes inside the mouse's body.

Compared with traditional bone imaging techniques, such as X-ray and CT, new fluorescent probes have many significant advantages. This allows researchers to clearly observe the shape of the mouse's whole body bones without harming the mouse.

It not only avoids the possible risks caused by ionizing radiation, but also dynamically observes the evolution of bone metabolism, osteoporosis and other diseases.


Near-infrared second zone optical probe in vivo multi-color imaging and bone imaging