[Shanghai: Strengthen targeted supervision in key areas and key varieties, and further promote on-site inspections of vaccine manufacturers in production] On November 9, the Shanghai Food and Drug Safety Commission issued the "Shanghai Fifteenth Five-Year Plan to Ensure Drug Safety and Promote High-Quality Development of the Pharmaceutical Industry." It mentioned that targeted supervision in key areas and key varieties should be strengthened. Improve the implementation of entrusted production responsibilities and risk sharing mechanisms, and consolidate the main responsibilities for quality and safety and the responsibilities specified in the entrusted production quality agreement. In-depth promotion of dispatched inspections of vaccine manufacturing companies in production. Implement full-coverage and key supervision on vaccines, blood products, advanced therapeutic drugs, sterile drugs, special drugs, segmented production varieties, etc., and strengthen risk prevention and control in key links such as data reliability, sterility assurance, deviation management, and change management. Strengthen the supervision of key medical device varieties such as implantable, sterile, and centralized procurement, formulate a "one product, one policy" supervision plan for innovative medical devices, and strengthen inspections of key raw material procurement, finished product inspection, and factory release. Carry out actions to improve the production quality management system of cosmetics companies, strengthen supervision of key products such as special cosmetics and cosmetics using new raw materials, and strengthen raw material management.